In Vitro Study Of  The Antibacterial  Activity of Diffrent Organic Extract Of Swertia Chirata Against Streptococcus Pyogenes 

S. N. Pandey: Research conception, experimental work and manuscript development. Fazal Ahmad: Assistance with the research work and manuscript preparation. Sanjay: Review and  editing.

Abstract

Swertia chirata is a popular medicinal plant native to the Himalayan region and has been widely used as herbal

medicine in India and other parts of the world. The aim of the present study was to evaluate the antibacterial activity

of different organic extracts of Swertia chirata against the pathogenic bacterium Streptococcus pyogenes. The

antibacterial activity of methanolic, ethanolic, chloroform and benzene extracts was evaluated at doses ranging from

0 to 600 μg using the disc diffusion method. The zone of inhibition was measured in millimetres using a Vernier

caliper. The extracts demonstrated antibacterial activity against Streptococcus pyogenes, with variation in the degree

of activity among the different extracts and doses. The findings indicate that organic extracts of Swertia chirata

possess potential antibacterial activity against Streptococcus pyogenes and may warrant further investigation for

their antimicrobial properties.